to disregard; to discount; to defy; to belittle; to think nothing of something; to make light of something; to hold something cheap
To defy the law/to take the law into one's own hands; to be no respecter of the law
To have no respect for freedom of speech; to take liberties with freedom of speech
Her parents seem to think nothing of our opinion; her parents seem to make light of our opinion; her parents seem to disregard our opinion
He is always reckless of his parents' advice
He always disregards the family of his wife
You should not discount young people
To treat one's colleagues as a bunch of nobodies
To laugh at adversities