1. a. The act or an instance of flowing, passing, or giving out. b. The act of circulating, distributing, or publishing by an office or official group: government issue of new bonds.

2. Something produced, published, or offered, as: a. An item or set of items, as stamps or coins, made available at one time by an office or bureau. b. A single copy of a periodical: the March issue of the magazine. c. A distinct set of copies of an edition of a book distinguished from others of that edition by variations in the printed matter. d. A final result or conclusion, as a solution to a problem. e. Proceeds from estates or fines. f. Something proceeding from a specified source: suspicions that were the issue of a deranged mind.

3. Offspring; progeny: died without issue.

4. a. A point or matter of discussion, debate, or dispute: legal and moral issues. b. A matter of public concern: refused to address the economic issues. c. The essential point; crux: the issue of how to provide adequate child care. d. A culminating point leading to a decision: bring a case to an issue.

5. A place of egress; an outlet: a lake with no issue to the sea.

6. Pathology. a. A discharge, as of blood or pus. b. A lesion, a wound, or an ulcer producing such a discharge.

7. Archaic. Termination; close.

1. To go or come out. See synonyms at appear.

2. To accrue as proceeds or profit: Little money issued from the stocks.

3. To be born or be descended.

4. To be circulated or published.

5. To spring or proceed from a source. See synonyms at stem1.

6. To terminate or result.

1. To cause to flow out; emit.

2. To circulate or distribute in an official capacity: issued uniforms to the players.

3. To publish: issued periodic statements.

1. In question; in dispute: "Many people fail to grasp what is really at issue here" (Gail Sheehy).

2. At variance; in disagreement.

1. To enter into controversy.

2. Law. To submit an issue for decision.