disadvantage; handicap
To be at a disadvantage compared with somebody
To be put at the greatest disadvantage
This new law will put unmarried couples at a disadvantage; This new law will be unfair to unmarried couples; This new law will disadvantage/penalize unmarried couples
He favoured his children over his wife in his will
He was handicapped by not being able to speak English
disadvantageous; unfavourable
It is very disadvantageous/unfavourable to small and medium-sized businesses